✦ LIBER ✦

Complestatin prevents apoptotic cell death: inhibition of a mitochondrial caspase pathway through AKT/PKB activation

✍ Scribed by Eok-Cheon Kim; Bong-Sik Yun; In-Ja Ryoo; Jeong-Ki Min; Moo Ho Won; Kwang-Soon Lee; Young-Myeong Kim; Ick-Dong Yoo; Young-Guen Kwon

Book ID: 116287606
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 433 KB
Volume: 313
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2003.11.104

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Celastrol inhibits growth and induces ap

Celastrol inhibits growth and induces apoptotic cell death in melanoma cells via the activation ROS-dependent mitochondrial pathway and the suppression of PI3K/AKT signaling

✍ Lee, Ju-Hye; Won, Yeong-Seon; Park, Ki-Hun; Lee, Mi-Kyung; Tachibana, Hirofumi; 📂 Article 📅 2012 🏛 Springer 🌐 English ⚖ 807 KB

SYUNZ-16, a newly synthesized alkannin d

SYUNZ-16, a newly synthesized alkannin derivative, induces tumor cells apoptosis and suppresses tumor growth through inhibition of PKB/AKT kinase activity and blockade of AKT/FOXO signal pathway

✍ Rong Deng; Jun Tang; Bing-Fen Xie; Gong-Kan Feng; Yu-Han Huang; Zong-Chao Liu; X 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 889 KB

## Abstract Alkannin is the major bioactive compound of Arnebia euchroma roots, which is used in many therapeutic remedies in Chinese traditional medicine. SYUNZ‐16 is a new derivative of alkannin. In this study, anticancer effects of SYUNZ‐16 on human lung adenocarcinoma cell line GLC‐82 and human

Caffeine activates the PI3K/Akt pathway

Caffeine activates the PI3K/Akt pathway and prevents apoptotic cell death in a Parkinson's disease model of SH-SY5Y cells

✍ Kazuhiro Nakaso; Satoru Ito; Kenji Nakashima 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 525 KB

The novel synthesized 2-(3-(methylamino)

The novel synthesized 2-(3-(methylamino)phenyl)-6-(pyrrolidin-1-yl)quinolin-4-one (Smh-3) compound induces G2/M phase arrest and mitochondrial-dependent apoptotic cell death through inhibition of CDK1 and AKT activity in HL-60 human leukemia cells

✍ Huang, 📂 Article 📅 2011 🏛 Spandidos Publications Ltd 🌐 English ⚖ 943 KB