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Complementation of melanocyte development in SOX10 mutant neural crest using lineage-directed gene transfer

✍ Scribed by Ling Hou; Stacie K. Loftus; Arturo Incao; Amy Chen; William J. Pavan

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
960 KB
Volume
229
Category
Article
ISSN
1058-8388

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## Abstract Summary: This study describes an in utero approach for overexpressing genes in a cell‐type directed manner. It uses an avian leukosis retroviral expression system coupled with a transgenic mouse line expressing the viral receptor __tv‐a__ from a tissue‐specific promoter (RCAS‐TVA system