𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Complementation of an hMSH2 defect in human colorectal carcinoma cells by human chromosome 2 transfer

✍ Scribed by Yoh Watanabe; Astrid Haugen-Strano; Asad Umar; Kanae Yamada; Hiromichi Hemmi; Yoshinori Kikuchi; Shoichi Takano; Yoichiro Shibata; J. Carl Barrett; Thomas A. Kunkel; Minoru Koi


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
303 KB
Volume
29
Category
Article
ISSN
0899-1987

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Growth inhibition due to complementation
✍ Yasunori Miyafuji; Xiaoling Zhong; Iichiro Uchida; Minoru Koi; Hiromichi Hemmi πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 257 KB

The transforming growth-beta receptor type II (TGF-beta RII) gene is one of the target genes of the DNA mismatch repair (MMR) defect. The human colorectal carcinoma cell line HCT116 has mutations in the hMLH1 gene and in the microsatellite region of the TGF-beta RII gene, both located on the short a

Human mismatch repair gene (hMSH2) produ
✍ Tie-Xiong Jin; Mutsuo Furihata; Ichiro Yamasaki; Masayuki Kamada; Sheng-Ben Lian πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 288 KB πŸ‘ 2 views

## Background: Several convincing studies have shown that the hmsh2 gene plays major roles in mismatch repair by recognizing mismatched bases and preventing mutations during dna replication. loss of this function may result in the accumulation of dna replication errors or even the mutator phenotype

Selective cytotoxicity of murine monoclo
✍ Rolf A. Stahel; Mack Mabry; Kert Sabbath; Jonathan A. Speak; Samuel D. Bernal πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 French βš– 581 KB

## Abstract LAM2 is a murine IgM monoclonal antibody (MAb) which binds strongly to the cell membrane of human lung small‐cell carcinoma (SCC) and squamous‐cell carcinoma but not to normal bone‐marrow cells. The cytotoxicity of this antibody in the presence of human complement was investigated __in

Apoptosis induction and cyclooxygenase-2
✍ Douglas J.E. Elder; Dawn E. Halton; Tracey E. Crew; Christos Paraskeva πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 French βš– 226 KB πŸ‘ 2 views

We determined the effect of the highly selective cyclooxygenase-2 (COX-2) inhibitor NS-398 on proliferation, apoptosis and COX-2 regulation in 3 pre-malignant human colorectal adenoma cell lines (RG/C2, AA/C1, RR/C1) and compared its effect on 3 colorectal carcinoma cell lines (HT29, KS, JW2). COX-2

Modulation of cisplatin sensitivity and
✍ Vicram Gupta; Jitesh P. Jani; Erling O. Emerson; Bing H. Xu; Domenic Scalamogna; πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 French βš– 593 KB

## Abstract This study was undertaken to elucidate the mechanism(s) of potentiation of cisplatin (CDDP) cytotoxicity by interferon α‐2a (IFN α‐2a) in human squamous carcinoma cell lines SCC‐25 and SCC‐4. IFN α‐2a treatment significantly increased the cytotoxicity of CDDP in both cell lines in a dos