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Complementation of a plasmid replication defect by autonomous incompatible plasmids in Staphylococcus aureus

✍ Scribed by Serban Iordănescu; Marietta Surdeanu

Book ID
119078688
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
521 KB
Volume
4
Category
Article
ISSN
0147-619X

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The Staphylococcus aureus chromosomal gene pcrA, identified by mutations, such as pcrA3, that affect plasmid pT181 replication, has been cloned and sequenced. The pcrA gene encodes a protein with significant similarity (40% identity) to two Escherichia coli helicases: the helicase II encoded by the