Glucocorticoid-receptor-gene defects and
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Monika Hala; Bernd L. Hartmann; GΓΌnther BΓΆck; Stephen Geley; Reinhard Kofler
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Article
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1996
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John Wiley and Sons
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French
β 674 KB
The application of glucocorticoids (GC') in human leukemia is based on apoptosis induction but is often hampered by GC resistance. To delineate resistance mechanisms, we examined 5 GC-resistant leukemic cell lines, termed CEM-C7.RI-R5, isolated from the GC-sensitive human acute-1-cell-leukemic line,