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Complementary duplication and deletion of 17 (pcen→p11.2): A family with a supernumerary chromosome comprised of an interstitially deleted segment

✍ Scribed by Friedman, J. M. ;Harrod, M. J. E. ;Howard-Peebles, P. N.


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
449 KB
Volume
44
Category
Article
ISSN
0148-7299

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## Abstract Smith–Magenis syndrome (SMS) is a disorder characterized by multiple congenital anomalies and behavior problems, including abnormal sleep patterns. It is most commonly due to a 3.5 Mb interstitial deletion of chromosome 17 band p11.2. Secretion of melatonin, a hormone produced by the pi