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Complement research: the impact of molecular genetics

✍ Scribed by Reinhard Burger

Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 349 KB
Volume: 7
Category: Article
ISSN: 0167-5699
DOI: 10.1016/0167-5699(86)90116-7

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## Abstract ## Background During recent years, we identified characteristic genetic alterations in sporadic hepatoblastoma (HB). These include loss of heterozygosity (LOH) at the chromosomal region 11p15.5, LOH on chromosome arms 1p and 1q, activating mutations in exon 3 of the β‐__catenin__ gene,