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Complement component C7 deficiency in two Spanish families

✍ Scribed by Sonia Barroso; Berta Sánchez; Antonia José Álvarez; Margarita López-Trascasa; Amparo Lanuza; Rafael Luque; Ingeborg Wichmann; Antonio Núñez-Roldán


Book ID
108781556
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
198 KB
Volume
113
Category
Article
ISSN
0019-2805

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DNA polymorphism of the human complement
✍ Eliecer Coto; Eduardo Martínez-Naves; Orlando Domínguez; Carlos López-Larrea 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 207 KB

A C7 cDNA probe detecting a TaqI restriction fragment length polymorphism has been used to examine the segregation of the "silent allele" (C7\*Q0) in two familial deficiencies. Carrier diagnosis in healthy children is possible when both parents are heterozygotes. Only one of these two families was i