Complement C6 deficiency delays degeneration and facilitates axonal regeneration and recovery in a model of peripheral nerve injury

Suppression of astroglial scar formation

Suppression of astroglial scar formation and enhanced axonal regeneration associated with functional recovery in a spinal cord injury rat model by the cell cycle inhibitor olomoucine

✍ Dai-Shi Tian; Zhi-Yuan Yu; Min-Jie Xie; Bi-Tao Bu; Otto W. Witte; Wei Wang 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 614 KB

## Abstract It is well established that axons of the adult mammalian CNS are capable of regrowing only a limited amount after injury. Astrocytes are believed to play a crucial role in the failure to regenerate, producing multiple inhibitory proteoglycans, such as chondroitin sulphate proteoglycans