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Complement (C3) metabolism in systemic lupus erythematosus in relation to the disease course

✍ Scribed by A. J. G. Swaak; A. Rooyen; C. Vogelaar; M. Pillay; E. Hack


Publisher
Springer
Year
1986
Tongue
English
Weight
648 KB
Volume
6
Category
Article
ISSN
0172-8172

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Complement (C3) metabolism in rheumatoid
✍ A. J. G. Swaak; H. Han; A. Rooyen; M. Pillay; C. E. Hack πŸ“‚ Article πŸ“… 1988 πŸ› Springer 🌐 English βš– 542 KB

Metabolic turnover studies of the third component of complement, C3, were performed in 23 patients with rheumatoid arthritis (RA) to get a direct insight in the dynamics of complement synthesis and catabolism. Results of these turnover studies were related to the serum level of the total amount of C

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## Abstract The in vivo metabolism of purified C3, the third component of complement, labeled with ^125^‐iodine (^125^I‐C3) was studied in 17 normal volunteers and in 24 patients with systemic lupus erythematosus (SLE). The latter had varying degrees of disease severity and differing clinical and s