Complement activation in patients with renal failure as detected through the quantitation of fragments of the complement proteins C3, C5, and factor B

Assessment of the potential pathogenicit

Assessment of the potential pathogenicity of type ii collagen autoantibodies in patients with rheumatoid arthritis. Evidence of restricted IgG3 subclass expression and activation of complement C5 to C5a

✍ W. C. Watson; M. A. Cremer; P. H. Wooley; A. S. Townes 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 616 KB

IgG subclass analysis by enzyme-linked immunosorbent assay of the autoantibody to native type I1 collagen, detected in 9 patients with classic or definite rheumatoid arthritis, demonstrated a predominance of IgG3 autoantibody. Gm allotyping revealed no obvious association with a particular phenotype