Complement activation associated with ADAMTS13 deficiency in human and murine thrombotic microangiopathy
✍ Scribed by Karpman, D.; Tati, R.; Kristoffersson, A.-C.; Ståhl, A.-L.; Rebetz, J.; Wang, L.; Licht, C.; Motto, D.
- Book ID
- 121779730
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 67 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0161-5890
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## Background: Thrombotic microangiopathy (TMA) encompasses a number of disorders with hemolytic anemia and thrombocytopenia, including thrombotic thrombocytopenic purpura (TTP). A deficiency in ADAMTS13 enzyme levels, along with an inhibitory antibody, is found in most patients with i
## Abstract Thrombotic microangiopathy (TMA) syndromes are a heterogeneous group of microvascular syndromes that are typically treated with plasma exchange and other adjunctive therapies. Important pathogenic factors, such as ADAMTS13 deficiency, define distinct subsets of TMA. New treatments for T