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Competitive Inhibition of γ-Aminobutyric Acid Synaptosomal Uptake by 4-(4′-Azidobenzoimidylamino)butanoic Acid

✍ Scribed by Godfrey Tunnicliff; That T. Ngo

Book ID
111172118
Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
252 KB
Volume
39
Category
Article
ISSN
0022-3042

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Chelation of endogenous membrane calcium
Chelation of endogenous membrane calcium inhibits γ-aminobutyric acid uptake in synaptosomes
✍ R. Tapia; C. Salazar 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 487 KB

In a previous work, we have demonstrated that calcium chelators induce the release of y-aminobutyric acid (GABA) from synaptosomes in a Na+-dependent manner and that this release is blocked by cations such as Mg2+, La3+, and ruthenium red. In the present study, we show that treatment of synaptosomes