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Competitive Inhibition of Colchicine Binding to Tubulin by Microtubule-Associated Proteins

✍ Scribed by Jacques Nunez, Arlette Fellous, Jacques Francon and Ana Maria Lennon

Book ID
123655749
Publisher
National Academy of Sciences
Year
1979
Tongue
English
Weight
849 KB
Volume
76
Category
Article
ISSN
0027-8424

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Previous studies have demonstrated that the microtubule-associated proteins MAP-2 and tau interact selectively with common binding domains on tubulin defined by the low-homology segments alpha (430-441) and beta (422-434). It has been also indicated that the synthetic peptide VRSKIGSTENLKHQPGGG corr