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Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate

โœ Scribed by Iakova, Polina; Wang, Guo-Li; Timchenko, Lubov; Michalak, Marek; Pereira-Smith, Olivia M; Smith, James R; Timchenko, Nikolai A

Book ID
110027463
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
694 KB
Volume
23
Category
Article
ISSN
0261-4189

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โœ Tanya Nekrasova; Dr. Audrey Minden ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 979 KB

## Abstract The serine/threonine kinase PAK4 regulates cytoskeletal architecture, and controls cell proliferation and survival. In most adult tissues PAK4 is expressed at low levels, but overexpression of PAK4 is associated with uncontrolled proliferation, inappropriate cell survival, and oncogenic