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Competition between histone H1 and HMGN proteins for chromatin binding sites

✍ Scribed by Catez, F.

Book ID
111744630
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
569 KB
Volume
3
Category
Article
ISSN
1469-221X

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We have investigated using the DNA binding fluorochromes 7-aminoactinomycin (7-AAMD) and 48,6diamidino-2-phenylindole (DAPI) as cytochemical probes for linker histone (H1)-chromatin interactions in situ. Human lymphocytes, permeabilized with digitonin, were exposed to increasing concentrations of so