Inversion of enantioselectivity in the h
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Simon Diezi; Andras Szabo; Tamas Mallat; Alfons Baiker
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Article
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2003
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Elsevier Science
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English
⚖ 178 KB
Asymmetric hydrogenation of ketopantolactone was studied on a 5 wt% Pt/Al 2 O 3 catalyst in the presence of cinchonidine and its O-methyl, -ethyl, -phenyl and -trimethylsilyl derivatives. Inversion of enantioselectivity with the latter two bulky substituents proved that in the enantiodifferentiating