A one-step route to 4-hydroxy-2,3-diaryl
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David J. Dodsworth; MarΓa-PΓa Caliagno; Ursula E. Ehrmann; Peter G. Sammes
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Article
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1980
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Elsevier Science
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French
β 206 KB
A new procedure for the synthesis of 2,3-diaryl-3,4-dihydro-4-hydroxy-1(2H)isoquinolones is described rn which the cis-isomer predominates. Dehydration leads to 2,4-diarylisocarbostyrils. The synthetic utility of metallated phthalide derivatives has recently received considerable attention for the