Compendium of Cycloaddition Reactions under High Pressure
✍ Scribed by Kiyoshi Matsumoto; Hiroshi Hamana; Hirokazu Iida
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 8 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract For the first time, uncatalyzed, high‐pressure (0.6 GPa) reactions with ketones have proven to be a powerful way to perform the three‐component __Strecker__ synthesis of __α__‐amino nitriles in high yields. Two types of double __Strecker__ reactions were achieved, but attempts to perfor
## Abstract The cycloaddition reaction of 2‐allenylindoles **2** with diethyl acetylenedicarboxylate **6** was undertaken under both thermal and high pressure reaction conditions, leading to carbazole derivatives **5**.
High‐pressure cycloaddition of 3,4‐dimethoxyfuran with 1,4‐benzoquinone, toluquinone and 2,3‐dimethoxy‐1,4‐benzoquinone show, at 7 kbar and room temperature, prevailing formation of __endo__‐isomers. Raising pressure (or temperature) results in a surprising increase of the __exo__‐isomer. By catalyt