Organization of transcriptional regulato
✍
Laura H. Saltman; Amjad Javed; John Ribadeneyra; Sadiq Hussain; Daniel W. Young;
📂
Article
📅
2005
🏛
John Wiley and Sons
🌐
English
⚖ 642 KB
## Abstract The osteoclast is a highly polarized multinucleated cell that resorbs bone. Using high resolution immunofluorescence microscopy, we demonstrated that all nuclei of an osteoclast are transcriptionally active. Each nucleus within the osteoclast contains punctately organized microenvironme