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Compartmentalization of polyamines in mammalian cells

โœ Scribed by M. Mach; P. Ebert; R. Popp; A. Ogilvie

Book ID
118316238
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
394 KB
Volume
104
Category
Article
ISSN
0006-291X

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## Abstract Chinese hamster ovary and rat myoblast cells resistant to the toxic action of methylglyoxal bis guanylhydrazone (MGBG), an antimitotic agent and inhibitor of polyamine synthesis, have been isolated by single step selection. Mutagenesis with ethyl methanesulfonate increases the recovery