Compartmental-model response function for dendritic trees

✍ Scribed by Paul C. Bressloff; John G. Taylor

• Book ID: 104660792
• Publisher: Springer-Verlag
• Year: 1993
• Tongue: English
• Weight: 851 KB
• Volume: 70
• Category: Article
• ISSN: 0340-1200
• DOI: 10.1007/bf00200833

✦ Synopsis

The membrane-potential response function of a dendritic tree is constructed using a compartmental model. It is shown that if certain conditions are imposed on the compartments at branching nodes and terminals of an arbitrary tree, then the response function has a simple matrix solution that may be evaluated explicitly. Moreover, it reduces to the corresponding path-integral expression of cable theory in the continuum limit. The response function in the presence of synaptic inputs with shunting is also constructed. The compartmental approach presented here provides a particularly simple method for exploring the effects of complex geometries on spatio-temporal pattern processing in neurons.