Mitotane associated with etoposide, doxo
โ
Alfredo Berruti; Massimo Terzolo; Anna Pia; Alberto Angeli; Luigi Dogliotti
๐
Article
๐
1998
๐
John Wiley and Sons
๐
English
โ 83 KB
๐ 2 views
BACKGROUND. The use of either mitotane or chemotherapy in the treatment of advanced adrenocortical carcinoma (ACC) has led to scanty and controversial results. The recent finding that mitotane is able to reverse in vitro multidrug resistance has provided a rational basis for combining this agent wit