## Abstract ## BACKGROUND Pediatric rhabdomyosarcomas (RMS) have a more advantageous prognosis after multimodality treatment compared with adult RMS, which might be related to a decreased sensitivity to chemotherapy in adults. Resistance to chemotherapy might be conveyed by the multidrug resistanc
Comparison of tic characteristics between children and adults
โ Scribed by Esther Cubo; Teresa Chmura; Christopher G. Goetz
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 175 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
There are limited data about clinical characteristics of tics in adults. We performed a video and chart retrospective longitudinal review of patients diagnosed with tics from a tertiary referral medical center to compare tic characteristics between adults and children. Tic severity in 40 children and 31 adults was assessed using the modified Rush videotape rating scale and the Yale global tic severity scale (YGTSS). Baseline tic severity scores were similar in adults when compared with children (P = 0.11). In followโup visits, compared to baseline total YGTSS scores were significantly reduced in both children (P < 0.003) and adults (P < 0.0009), but children were less frequently treated with medications for tics (P = 0.004) when compared with adults. Tic phenomenology and severity were similar between children and adults, but pharmacological tic management was different, perhaps reflecting a practice trend to avoid medications in children. ยฉ 2008 Movement Disorder Society
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