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Comparison of three methods for pharmacokinetic screening in rats using LC-MS-MS

โœ Scribed by S. Briem; E. Eklund; G. Williams; J. Brunvoll

Publisher
Springer
Year
2002
Tongue
English
Weight
442 KB
Volume
55
Category
Article
ISSN
0009-5893

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Metabolite profiling study of propranolo
Metabolite profiling study of propranolol in rat using LC/MS/MS analysis
โœ Francis Beaudry; J. C. Yves Le Blanc; Michel Coutu; Isabelle Ramier; Jean-Pierre ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 116 KB ๐Ÿ‘ 1 views

Metabolite profiling is one of the most challenging fields in applied mass spectrometry. Mass spectrometry was used to characterize the metabolites of propranolol, a beta-adrenergic receptor antagonist containing numerous oxidation sites. Propranolol is extensively metabolized, with most metabolites