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Comparison of the seroprevalence of human metapneumovirus and human respiratory syncytial virus

✍ Scribed by Takashi Ebihara; Rika Endo; Hideaki Kikuta; Nobuhisa Ishiguro; Hiroaki Ishiko; Kunihiko Kobayashi

Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 57 KB
Volume: 72
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.10572

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✦ Synopsis

Abstract

Human metapneumovirus (hMPV) is a virus that induces human respiratory syncytial virus (hRSV)‐like illnesses, ranging from upper respiratory tract infection to severe bronchiolitis and pneumonia. The 100 serum samples from children aged 1 month to 5 years were tested for the presence of hMPV and hRSV antibodies using an indirect immunofluorescence assay and a neutralizing‐antibody assay, respectively. The seroprevalence of hMPV was significantly lower than that of hRSV in children over 4‐months‐old (43% vs. 60%, P < 0.025), and the difference was particularly notable between the ages of 4 months and 1 year (11% vs. 48%, P = 0.006). The results suggest that primary infection with hMPV occurs somewhat later than that with hRSV. J. Med. Virol. 72:304–306, 2004. © 2004 Wiley‐Liss, Inc.

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