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Comparison of the rat and mouse hippocampal slice preparations for the detection of seizure liability

โœ Scribed by Jennifer Chen; Alison Easter; Carlos Fonck; Russ Bialecki

Book ID
113941931
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
56 KB
Volume
62
Category
Article
ISSN
1056-8719

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The action of bath applied NPY (1-1,000 nM) was investigated on hippocampal slices of the rat with extra-and intracellular recording. Neuropeptide Y (NPY) at 10-1,000 nM caused a concentration-dependent, longlasting reduction of excitatory postsynaptic potentials (EPSPs) in the hippocampal subfield