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Comparison of the protective effects of amifostine and dexrazoxane against the toxicity of doxorubicin in spontaneously hypertensive rats

✍ Scribed by Eugene H. Herman; Jun Zhang; Douglas P. Chadwick; Victor J. Ferrans

Publisher
Springer
Year
2000
Tongue
English
Weight
87 KB
Volume
45
Category
Article
ISSN
0344-5704

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## Abstract The usefulness of doxorubicin (DXR) is limited by its cardiotoxicity. In order to improve future DXR therapy by using a new antioxidant agent, an experimental study was designed. This study was undertaken to determine whether DXR‐induced cardiotoxicity is prevented by erdosteine, a muco