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Comparison of the Prophylactic Effect of Silymarin and Deferoxamine on Iron Overload-Induced Hepatotoxicity in Rat

โœ Scribed by Hossein Najafzadeh; Mohammad Razi Jalali; Hassan Morovvati; Farnaz Taravati

Book ID
107688371
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
134 KB
Volume
6
Category
Article
ISSN
1556-9039

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โœ M. Younes; I. Eberhardt; R. Lemoine ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 587 KB

To study the effect of iron-overload on hepatic lipid peroxidation, two rat models of haemochromatosis were employed: in the first model resembling secondary haemochromatosis, repeated i.p. injections with Fe-dextran led to an accumulation of Fe in Kupffer cells, while in the second model resembling