Predicting rodent carcinogenicity using
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Jonathan S. Schildcrout; Barry H. Margolin; Errol Zeiger
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Article
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1999
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John Wiley and Sons
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English
β 53 KB
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In vitro sister chromatid exchange (SCE) and chromosome aberration (ABS) tests have been extensively used to identify potential rodent carcinogens. A number of measures of potency were developed to describe in vitro SCE and ABS test results: the dose needed to induce a unit increase over the control