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Comparison of the polymorphic modifications of famotidine

✍ Scribed by Béla Hegedüs; Péter Bod; Kálmán Harsányi; Imre Péter; Alajos Kalman; Laszlo Parkanyi

Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
377 KB
Volume
7
Category
Article
ISSN
0731-7085

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✦ Synopsis

The polymorphic modifications of famotidine are described and characterized by their spectroscopic (infrared, X-ray) and some physico-chemical data. In addition to the standard physico-chemical data (melting point, solubility, bulk density) some further properties influencing its use in pharmaceutical technology are also characterized. The methods used to prepare the morphologically homogeneous modifications are also given.

📜 SIMILAR VOLUMES

Characterization and selective crystalli
Characterization and selective crystallization of famotidine polymorphs
✍ Jie Lu; Xiu-Juan Wang; Xia Yang; Chi-Bun Ching 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 327 KB

Famotidine crystallizes in two different polymorphic forms: the metastable polymorph B and the stable polymorph A. In this work, solid characterization for both polymorphs has been conducted in detail. The solubility, metastable zone width and interfacial energy of both polymorphs in different solve