Comparison of the pharmacokinetics of lamotrigine in patients with chronic renal failure and healthy volunteers
β Scribed by R. Wootton; J. Soul-Lawton; P. E. Rolan; C. T. C. Fook Sheung; J. D. H. Cooper; J. Posner
- Book ID
- 108640007
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 440 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0306-5251
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π SIMILAR VOLUMES
The pharmacokinetics of diltiazem were studied in seven patients with chronic renal failure (CRF) not requiring dialysis and in three healthy volunteers after a rapid i.v. infusion of 20mg. Mean plasma concentrations at the end of infusion were 3.15 times higher in patients with CRF than in healthy
Methods: We investigated the pharmacokinetics of quinine (Qn) following administration of a single oral dose of 600 mg Qn sulphate in six male Thai patients with a moderate degree of chronic renal failure (CRF), and six male Thai subjects with normal renal function. ## Results: The drug was well