Furosemide solution was orally administered to 21 healthy adult males to determine dose proportionality over the dose range used and the reproducibility of disposition following a repeated dose. Furosemide solution was given in doses of 20,40, and 80mg, with the 40 mg dose repeated once. Blood was c
Comparison of the pharmacokinetics of diazepam after single and subchronic doses
β Scribed by U. Klotz; K. H. Antonin; P. R. Bieck
- Publisher
- Springer
- Year
- 1976
- Tongue
- English
- Weight
- 704 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0031-6970
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The pharmacokinetic parameters of ibuprofen enantiomers after a single 600 mg dose and repeated 3 x 400 mg doses of Nurofen@ were determined in 12 healthy volunteers. Terminal half-lives were similar for both enantiomers, but plasma levels of S-ibuprofen were higher than those of R-ibuprofen, due to
Pharmacokinetic profiles of imipramine and a newer tetracyclic antidepressant, maprotiline, were studied in elderly (75-83 years of age) subjects who were given a single oral dose of 125 and 175mg, respectively, of these drugs. The apparent elimination half-life of imipramine was 20.8 -34.9 h (mean