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Comparison of the NMR solution structures of cyclosporin A determined by different techniques

✍ Scribed by Ruth Pachter; Russ B Altman; Jerzy Czaplicki; Oleg Jardetzky


Book ID
107798541
Publisher
Elsevier Science
Year
1991
Weight
656 KB
Volume
92
Category
Article
ISSN
0022-2364

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Solution structures of the DP IV (CD26)
✍ Ulrich L. GΓΌnther; James L. Sudmeier; Simon J. Coutts; Roger J. Snow; Randall W. πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 917 KB

## Abstract L‐Val‐L‐boroPro, a potent DP IV (CD26) inhibitor, and its non‐inhibitory diastereomer L‐Val‐D‐boroPro, were studied by 1D ^1^H and ^11^H NMR and by 2D ^1^H NMR methods in aqueous solution. Complete 1D ^1^H NMR fine structures were computer analyzed to obtain the ^1^H chemical shifts and