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Comparison of the malignant phenotype and genotype of the human androgen-independent cell line DU 145 and a subline derived from metastasis after orthotopic implantation in nude mice

✍ Scribed by Axel Bex; Bernd Wullich; Volker Endris; Thomas Otto; Klaus Rembrink; Michael Stöckle; Herbert Rübben

Book ID
114134967
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
342 KB
Volume
124
Category
Article
ISSN
0165-4608

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Experiments have been performed to clarify whether LHRH agonists might decrease growth of hormone-unresponsive prostate cancer in vivo. Male nude mice were injected s.c. with the human androgen-independent prostate tumor DU 145 cells; osmotic minipumps releasing the LHRH agonist Zoladex (LHRH-A) for