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COMPARISON OF THE LIPID-LOWERING EFFECTS OF NICOTINIC ACID AND 2,5-DIMETHYLPYRAZINE IN RATS

✍ Scribed by KEISUKE KAGAMI; KENJI ONDA; TOSHIHIKO HIRANO; KITARO OKA

Book ID
111338342
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
293 KB
Volume
15
Category
Article
ISSN
1065-7258

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## Abstract Squalene epoxidase is a microsomal enzyme that catalyzes the conversion of squalene to 2,3‐oxidosqualene and is an important control site in the cholesterol synthetic pathway. FR194738 is a potent inhibitor of hepatic squalene epoxidase from dogs, hamsters, and rats with IC~50~ values o