The inhibition by 6-diazo-5-oxo-L-norleu
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Randall C. Willis; J. Edwin Seegmiller
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Article
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1977
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John Wiley and Sons
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English
⚖ 883 KB
## Abstract The rapid catabolism of glutamine by the cultured human lymphoblast line WI‐L2 can be inhibited greater than 95% by incubation of cell suspensions with 6‐diazo‐5‐oxo‐L‐norleucine (DON). The inhibition persists for at least four hours after removal of DON from the cell suspension. The ex