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Comparison of the efficacy and safety of single-agent and doublet chemotherapy in advanced non-small cell lung cancer in the elderly: A meta-analysis

✍ Scribed by Gaetan Des Guetz; Bernard Uzzan; Patrick Nicolas; Dominique Valeyre; Georges Sebbane; Jean-François Morere


Book ID
119222905
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
263 KB
Volume
84
Category
Article
ISSN
1040-8428

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We have carried out a randomized phase Ill study in 105 patients with advanced nonsmall cell lung cancer, comparing a fourdrug cisplatin-mitomycin-based combination chemotherapy regimen t o sequential single-agent therapy. The combination chemotherapy regimen consisted of mitomycin C (10 mg/m2), vin