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Comparison of the effect of irindalone, a novel serotonin 5-HT2 antagonist and ketanserin on mechanical responses of rat thoracic aorta

✍ Scribed by Erich O. Mikkelsen; Niels C.B. Nyborg; Kåre T. Jensen; Vita Boeck

Book ID
115881265
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
216 KB
Volume
149
Category
Article
ISSN
0014-2999

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The effect of the enantiomers of a novel 5-HT2 receptor antagonist, (~)-(1R,3S)-1- [2-[4-[3-(p-fluorophenyl)-l-indanyll-piperazinyllethyll-2imidazolidinone, was studied on serotonin (5-HT), noradrenaline (NA), potassium (K+), and calcium (Ca2+)-induced contractions in isolated rat thoracic aorta. Th