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Comparison of the effect of different immunological adjuvants on the antibody and T-cell response to immunization with MUC1-KLH and GD3-KLH conjugate cancer vaccines

โœ Scribed by Soo Kie Kim; Govindaswami Ragupathi; Cristina Musselli; Sun-Ju Choi; Yoon Sun Park; Philip O Livingston


Book ID
117433607
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
129 KB
Volume
18
Category
Article
ISSN
0264-410X

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โœ Carmen Scheibenbogen; Dirk Schadendorf; Nikolaos E. Bechrakis; Dirk Nagorsen; Ud ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 316 KB

## Abstract Immunologic adjuvants are used to augment the immunogenicity of MHC class Iโ€“restricted peptide vaccines, but this effect has rarely been systematically evaluated in a clinical trial. We have investigated, in a phase I study, whether addition of the 2 adjuvants GMโ€CSF and KLH can enhance