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Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases

โœ Scribed by E.Lucile White; William B. Parker; Lisa J. Macy; Sue C. Shaddix; George McCaleb; John A. Secrist III; Robert Vince; William M. Shannon


Book ID
115762509
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
466 KB
Volume
161
Category
Article
ISSN
0006-291X

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Inhibition of human immunodeficiency vir
โœ Milbrey C. Starnes; Yung-Chi Cheng ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer ๐ŸŒ English โš– 840 KB

The 2',3'-dideoxynucleoside triphosphates (ddNTPs) are potent substrate analog inhibitors of human immunodeficiency virus (HIV) reverse transcriptase and have clinical utility in the treatment of acquired immunodeticiency syndrome. Several issues regarding the interaction of these compounds with HIV