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Comparison of the daytime sleep and performance effects of zolpidem versus triazolam

✍ Scribed by Thomas J. Balkin; Vincent M. O'Donnell; Nancy Wesensten; Una McCann; Gregory Belenky


Publisher
Springer
Year
1992
Tongue
English
Weight
790 KB
Volume
107
Category
Article
ISSN
0033-3158

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Rebound insomnia is a transient intense worsening of sleep usually appearing within 3 days from the abrupt discontinuation of benzodiazepines (mainly short-acting), following long term use and abuse of these hypnotics. Zolpidem is an imidazopyridine, that binds selectively at mi-receptor subtypes wi

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The effects of a short-acting benzodiazepine hypnotic, triazolam (0.5 mg), on sleep, performance, and arousal threshold were assessed in 20 male poor sleepers (age 21 +/- 2.37 years). Following in a laboratory screening night, all subjects received placebo for 3 nights (single-blind), ten received t