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Comparison of the ability of phospholipids from rat liver lysosomes to reconstitute glucocerebrosidase

โœ Scribed by Alakananda Basu; Robert H. Glew; John R. Wherrett; Srebrenka Huterer

Book ID
115706950
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
525 KB
Volume
245
Category
Article
ISSN
0003-9861

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Mannose-terminal glucocerebrosidase prepared by exoglycosidase digestion of human placental glucocerebrosidase is reported effective in the treatment of patients with type 1 Gaucher's disease [Barton et al. (1 991 1; N Engl J Med 324:1464-I 4701. However, the amount of enzyme that is necessary for t