Comparison of supercritical carbon dioxide extraction with solvent extraction of nonacosan-10-ol, α-amyrin acetate, squalene and stigmasterol from medicinal plants
✍ Scribed by Young Hae Choi; Jinwoong Kim; Min Jeong Noh; Eun Sun Choi; Ki-Pung Yoo
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 129 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0958-0344
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✦ Synopsis
Supercritical carbon dioxide extraction was carried out in the temperature range 35 to 60°C and from 10 to 30 MPa in order to obtain phytochemical components from several medicinal plants. These were nonacosan-10-ol (1) from the aerial parts of Ephedra sinica, ␣-amyrin acetate (2) from the root bark of Morus alba, and squalene (3) and stigmasterol (4) from the entire plant of Spirodela polyrhiza. For comparison, Soxhlet extraction with nhexane was also carried out for these constituents. In the case of supercritical carbon dioxide extraction of 1, 2 and 4, the extraction yields tended to increase with increased temperature when the pressure was above 20 MPa. However, extraction yields were maximal at 40°C or 50°C below 15 MPa. When the amounts of extracts obtained by supercritical extraction are compared with those by Soxhlet extraction using n-hexane, it is apparent that supercritical carbon dioxide extraction can be used as an alternative method in the case of squalene and nonacosan-10-ol.