Comparison of stress indices in gauging clinical activity in patients with inflammatory bowel disease

✍ Scribed by Linda C. Duffy; Maria A. Zielezny; James R. Marshall; Milton M. Weiser; James F. Phillips; Tim E. Byers; Pearay L. Ogra; Saxon Graham

• Publisher: Springer
• Year: 1992
• Tongue: English
• Weight: 584 KB
• Volume: 5
• Category: Article
• ISSN: 0894-9867
• DOI: 10.1002/jts.2490050409

✦ Synopsis

Stress indices are wifely available but few have been validated or used for monitoring clinical disease activity in chronic inflammatory disorders. One hundred twenty-three outpatients with inflammatory bowel disease (IBD) participated in this prospective investigation. Stress events (major events, daily strains, perceived stress) and disease activity were monitored for sir consecutive follow-ups using standardized instruments. We present effect estimates of daily strains on clinical disease activity separately from the effect of major stress events. Our results indicate that the stress measures were moderately correlated, correlation coefficients ranged from .64 to .66. In relation to disease, self-perceived stress using a stress ladder (r = .31, p < ,001) was comparable to probing stress event chectclists (major events: r = .34, p < .001; daily strains: r = .20, p = NS). A multiple linear regression analysis revealed that each of the three methodr of evaluating stress makes a significant contribution, even afrer adjustment for potential con founders. No substantial increase in the proportion of explained variance was evident in an analysis based on a