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Comparison of soluble and membrane-bound pyroglutamyl peptidase I activities in rat brain tissues in the presence of detergents

✍ Scribed by F Alba; J.C Arenas; M.A Lopez

Book ID
113237621
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
509 KB
Volume
29
Category
Article
ISSN
0143-4179

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Thyrotropin-Releasing hormone (TRH)-degrading pyroglutamyl peptidase I (PGP I) and prolylendopeptidase (PE) activities have been demonstrated in rat insulinoma RINm 5F cell line. These two enzymes catalyze the conversion of TRH to Histydyl-Proline-Diketopiperazine and to acid TRH respectively. After