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Comparison of serum concentrations of methotrexate after various routes of administration

✍ Scribed by M. Freeman-Narrod; B. J. Gerstley; P. F. Engstrom; R. S. Bornstein

Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
355 KB
Volume
36
Category
Article
ISSN
0008-543X

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## Abstract The pharmacokinetics and tissue distribution of methotrexate (MTX) were investigated after intravenous (i.v.) injection of free MTX (treatment I), MTX‐loaded proliposomes (treatment II), and empty proliposomes mixed manually with free MTX (treatment III), 8 mg kg^βˆ’1^, to rats using an H