Comparison of second- and third-generation hepatitis C virus enzyme- linked immunosorbent assays in a low-risk blood donor population
β Scribed by B. C. Dow; E. A. Follett; F. Davidson; M. Calmann
- Book ID
- 114440213
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 237 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0372-1248
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The prevalence of antibodies to the hepatitis C virus (HCV) was determined in 498 hemodialysis patients from three german dialysis units, 121 staff members and 42 family members using an enzyme-linked immunosorbent assay (ELISA) of the second generation which detects antibodies to a structural (C22)
In a cohort of 483 blood donors positive for antibody to hepatitis C virus on second-generation enzyme-linked immunosorbent, the confirmatory second-generation recombinant immunoblot assay (Ortho Diagnostic Systems) was positive in 172 cases (36%), indeterminate in 113 (23%), and negative in 198 (41