Plasma protein binding of celecoxib in m
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Susan K. Paulson; Todd A. Kaprak; Christopher J. Gresk; Douglas M. Fast; Mike T.
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Article
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1999
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John Wiley and Sons
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English
β 151 KB
π 2 views
The plasma protein binding of celecoxib was determined for animals and humans using in vitro and ex vivo methods. Eight, healthy, human volunteers (three male, five female, 20-39 years) received celecoxib (600 mg) BID for 7 days, blood samples were collected and concentrations of bound and unbound c