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Comparison of propranolol-binding plasma proteins in sheep with those in humans, dogs and rats

✍ Scribed by Martin D. Hill; Pamela R. Briscoe; Fred P. Abramson


Book ID
115781147
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
838 KB
Volume
38
Category
Article
ISSN
0006-2952

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The plasma protein binding of celecoxib was determined for animals and humans using in vitro and ex vivo methods. Eight, healthy, human volunteers (three male, five female, 20-39 years) received celecoxib (600 mg) BID for 7 days, blood samples were collected and concentrations of bound and unbound c