Comparison of primary osteosarcoma of flat bones with secondary osteosarcoma of any site

✍ Scribed by Charles B. Pratt; William H. Meyer; Bhaskar N. Rao; Alberto S. Pappo; Irvin D. Fleming; Xiaolong Luo; Alvida Cain; Sue C. Kaste; Patricia D. Shearer; Jesse J. Jenkins III

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 105 KB
• Volume: 80
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/(sici)1097-0142(19970915)80:6<1171::aid-cncr22>3.0.co;2-4

✦ Synopsis

and The Unidisease resections. Chemotherapy with single or combinations of agents rarely versity of Tennessee, Memphis, College of Medyielded responses for primary flat bone or secondary osteosarcomas. icine, Memphis, Tennessee.

CONCLUSIONS. Outcome for both groups of patients was poor due to metastases

2 Department of Surgery, St. Jude Children's and failure of local control. Sixteen of the 27 patients with primary osteosarcoma Research Hospital, and The University of Tenof flat bones died of their tumor; an additional patient died of doxorubicin-related nessee, Memphis, College of Medicine, Memcardiomyopathy and had microscopic disease in the primary site at autopsy. Thirphis, Tennessee.

teen of the 18 patients with secondary osteosarcoma died of their second metastatic 3 Department of Biostatistics, St. Jude Chilcancer, 2 additional patients died of doxorubicin-related cardiomyopathy/coccididren's Research Hospital, and The University oidomycosis, and another of acute renal toxicity.